Amantadine guide: uses, side effects, dosing, and buying tips

Amantadine is a prescription medicine used mostly for Parkinson's symptoms, drug‑induced movement problems, and sometimes fatigue in multiple sclerosis. It was also an early antiviral against influenza A, but resistance makes that use rare today. This short guide helps you understand what amantadine does, common side effects, dosing basics, safety checks, and how to buy it wisely.

How amantadine works and when it's used

Amantadine boosts dopamine activity and affects other brain systems, which can reduce tremor, stiffness, and involuntary movements. Doctors often add it when patients have dyskinesia or need extra symptom control alongside other Parkinson drugs. Neurologists also prescribe it off‑label for MS fatigue. If you had influenza A in the past, your provider might mention it, but modern flu treatment usually uses other antivirals.

Practical tips: dosing, safety, and buying

Typical adult dosing starts low and goes up as needed. Many adults take 100 mg once or twice a day; some need 200 mg a day split into two doses. Your doctor will adjust dose for older adults and people with kidney problems because amantadine is cleared by the kidneys. Don’t change the dose or stop suddenly — sudden withdrawal can worsen symptoms.

Watch for these side effects: restless sleep, dizziness, dry mouth, nausea, and confusion. Hallucinations, agitation, or sudden mood changes need prompt medical attention. Long‑term use can cause a purple mottling of the skin called livedo reticularis; it’s not always harmful but tell your doctor.

Drug interactions matter. Combining amantadine with anticholinergic drugs or other stimulants can raise side effect risk. If you take blood pressure meds, psychiatric medicines, or other Parkinson drugs, review interactions with your prescriber or pharmacist.

Before you start, ask for a kidney function test and a medication review. Avoid driving or heavy machinery until you know how the drug affects you. Alcohol can make dizziness and sleepiness worse, so limit drinking when you start or change dose.

Buying amantadine: what to check

Buy from licensed pharmacies only. Online pharmacies should require a prescription, show clear contact info, and display licensing. Watch for prices that look too good to be true—counterfeit pills are a risk. If ordering online, check reviews, confirm secure payment, and ask your doctor to verify the pharmacy if unsure.

If side effects or benefits are unclear after a few weeks, talk to your doctor about dose changes or alternatives. Alternatives depend on the problem you treat — different Parkinson drugs, or specific antivirals for flu. Keep notes on symptom changes; concrete examples help your clinician choose the next step.

Expect to wait a few days to a few weeks to see benefit in movement or fatigue. Small wins like less stiffness or fewer involuntary jerks show in the first week but full effect may take longer. Women who are pregnant or trying to conceive should tell their doctor — amantadine may not be recommended. Keep a simple daily log: dose, sleep, mood, and any thinking. That record speeds adjustments.